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Signaling through the phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) axis is responsible for aerobic glycolysis mediated by glucose transporter in epidermal growth factor receptor (EGFR)-mutated lung adenocarcinoma

Given the paradoxical function of cholesterol that has been reported, the benefits of targeting specific aspects of cholesterol metabolism to improve the antitumor immune response, requires further exploration

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